Kevin Lynn Campbell
|Office||W465 Duff Roblin|
My research utilizes molecular biology techniques in conjunction with physiological and metabolic studies to study the hemoglobin oxygen-affinity, energetics and evolutionary physiology of shrews and moles (and other semi-aquatic mammals), with a focus on the specializations these insectivores have evolved to cope with hypoxia/hypercapnia and temperature. Our lab is also actively spearheading several projects that are focused on elucidating the functional/structural properties and physiochemical evolution of authentic gene products resurrected from DNA sequences of extinct mammalian species (e.g. woolly mammoth, woolly rhinoceros and Steller's sea cow). More information can be found at my personal website .
Research InterestsPaleophysiology of extinct Pleistocene mammals, Physiology, Evolutionary, molecular and environmental physiology of mammals, Evolutionary physiology of fossorial and semi-aquatic insectivores
- Gaudry, MJ and KL Campbell (2017). Evolution of UCP1 transcriptional regulatory elements across the mammalian phylogeny. Frontiers in Physiology 8, 670.
- Gaudry, M.J., M. Jastroch, J.R. Treberg, M. Hofreiter, J.L.A. Paijmans, J. Starrett, N. Wales, A.V. Signore, M.S. Springer, and K.L. Campbell (2017). Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades. Science Advances 3 (7), E1602878.
- He, K., A. Shinohara, K.M. Helgen, M.S. Springer, J. Xue-Long and K.L. Campbell (2017). Talpid mole phylogeny unites shrew moles and illuminates overlooked cryptic species diversity. Molecular Biology and Evolution 34 (1), 78-87.
- Campbell, K.L. and M. Hofreiter (2015). Resurrecting phenotypes from ancient DNA sequences: promises and perspectives. Canadian Journal of Zoology 93 (9), 701-710.
- Springer, M.S., A.V. Signore, J.L.A. Paijmans, D.P. Domning, J. Velez-Juarbe, C. Bauer, K. He, L. Crerar, P.F. Campos, W.J. Murphy, R.M. Meredith, J. Gatesy, E. Willerslev, R.D.E. MacPhee, M. Hofreiter and K.L. Campbell. (2015). Interordinal gene capture, the phylogenetic position of Steller's sea cow based on molecular and morphological data, and the macroevolutionary history of Sirenia. Molecular Phylogenetics and Evolution 91 (10), 178-193.